If you select a range of frames in the Timeline view, you can swap drawings over the entire selected range of frames at the same time. However, there are two approaches to doing this, with two different results.
Drawing Picker, Library View or Keyboard Shortcuts
If you select a range of frames in the Timeline view, then use the Drawing Picker view, the Library view or the [ and ] keyboard shortcuts to swap drawings, the drawing in every frame in the selected range will be replaced with the new drawing. However, subsequent drawings will not be substituted, even if they are part of the same exposure. This will make the selected range of frames into its own exposure, breaking it from the exposure before and after the selection.
Timeline View
If you select a range of frames in the Timeline view, then use the Parameters column to swap drawings, the every frame in the selected range will be replaced with the new drawing up and until the end of the last exposure in the selection.
