By default, a guide will only display its horizon line, its vanishing point, and its axes relative to your mouse cursor's position. To help you lay out the objects in your drawing, you can also enable reference lines. Reference lines are multiple semi-transparent lines that are drawn in parallel to your axes and from your vanishing points, at an equal distance or angle from each other, to cover your entire drawing space with visual guides.
When using reference lines, you can decide the amount of lines that display in your drawing space. If you have too many reference lines, they will be very close to each other and your drawing space might feel cluttered, but if you have too few, you might not always have a reference line close enough to the stroke you wish to draw to help serve as a reference.